Publications

Robles-Holmes, H., Coyner, A. S., Campbell, J. P., & Nudleman, E. (2023). Imaging Features Associated with Persistent Avascular Retina in ROP. Ophthalmology. 2023 Oct; S0161-6420(23)00711-X. PMID: 37805003

doi: https://doi.org/10.1016/j.ophtha.2023.09.032

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Chen JS, Marra KV, Robles-Holmes HK, Ly KB, Miller J, Wei G, Aguilar E, Bucher F, Ideguchi Y, Coyner AS, Ferrara N, Campbell JP, Friedlander M, Nudleman E.  Applications of Deep Learning: Automated Assessment of Vascular Tortuosity in Mouse Models of Oxygen-Induced Retinopathy. Ophthalmol Sci. 2023 Oct;100338.

doi: https://doi.org/10.1016/j.xops.2023.100338

Perez EA, Scott NL, Russell JF. Improved Visual Outcomes after Severe Open-Globe Injuries Associated with Perioperative Vitreoretinal Evaluation. Ophthalmol Retina. 2023 Sep;7(9):771-778. PMID: 37148970.

doi: https://doi.org/10.1016/j.oret.2023.04.015

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Lin AC, Kalaw FGP, Schönbach EM, Song D, Koretz Z, Walker E, Breazzano MP, Scott NL, Borooah S, Ferreyra H, Spencer DB, Goldbaum MH, Nudleman ED, Freeman WR, Toomey CB. The Sensitivity of Ultra-Widefield Fundus Photography Versus Scleral Depressed Examination for Detection of Retinal Horseshoe Tears. Am J Ophthalmol. 2023 Jul; 17;255:155-160. PMID: 37468086

doi: https://doi.org/10.1016/j.ajo.2023.07.010

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Yassin SH, Wang Y, Freeman WR, Heinke A, Walker E, Nguyen T, Bartsch DG, An C, Borooah S. Efficacy and accuracy of artificial intelligence to overlay multimodal images from different optical instruments in patients with retinitis pigmentosa. Clin Exp Ophthalmol. 2023 Apr 26. PMID: 37102206.

doi: https://doi.org/10.1111/ceo.14234

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Dastgheyb, N., Kline, L. B., Dhital, R., Lee, R. R., Choi, S. I., & Spencer, D. B. (2023). Optic Tract Involvement in a Patient With Relapsing Polychondritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2023 Apr 19. PMID: 37075261

doi: https://doi.org/10.1097/WNO.0000000000001861

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Schönbach EM, Knight DK, Wu CY, Arevalo JF, Bittencourt de Souza L, Cheng L, Chhablani J, Delalibera Pacheco K, Feucht N, Kozak I, Maia A, Maier M, Roizenblatt M, Smiddy WE, Sobol WM, Freeman WR. Direct macular hole manipulation results in high success rate in secondary macular hole repair. Retina. 2023 Apr 1;43(4):555-559. PMID: 36727800.

doi: https://doi.org/10.1097/iae.0000000000003712

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Kalaw FG, Warter A, Cavichini M, Knight D, Li A, Deussen D, Galang C, Heinke A, Borooah S, Baxter SL, Bartsch DU, Cheng L, and Freeman WR. Retinal tissue and microvasculature loss in COVID-19 infection. Scientific Reports. 2023 March 29;13(1):5100. PMID: 36991025

doi: https://doi.org/10.1038/s41598-023-31835-x

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Kalaw FGP, Ignacio JCI, Wu CY, Ferreyra H, Nudleman E, Baxter SL, and Freeman WR, Borooah S. Pentosan polysulfate sodium (Elmiron) maculopathy: a genetic perspective. Retina. 2023 Mar 28. PMID: 36996461.

doi: https://doi.org/10.1097/iae.0000000000003794

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Freeman WR, Bandello F, Souied E, Guymer RH, Garg SJ, Chen FK, Rich R, Holz FG, Patel SS, Kim K, López FJ, and BEACON Study Group. Randomized Phase IIb Study of Brimonidine Drug Delivery System Generation 2 for Geographic Atrophy in Age-Related Macular Degeneration. Ophthalmology Retina. 2023 Mar 10;S2468-6530(23)00097-0. PMID: 36906177.

doi: https://doi.org/10.1016/j.oret.2023.03.001

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Bakhoum CY, Madala S, Long CK, Adabifirouzjaei F, Freeman WR, Goldbaum MH, DeMaria AN, and Bakhoum MF. Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease. Eye (Lond). 2023 Mar;37(4):764-767. doi: 10.1038/s41433-022-02038-x.PMID: 35411111.

doi: https://doi.org/10.1038/s41433-022-02038-x

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Cavichini, M., Bartsch, D. G., Warter, A., Singh, S., An, C., Wang, Y., Zhang, J., Nguyen, T., & Freeman, W. R. Accuracy and Time Comparison Between Side-by-Side and Artificial Intelligence Overlayed Images. Ophthalmic surgery, lasers & imaging retina. 2023 Feb 1; 54(2), 108–113. PMID: 36780638

doi: https://doi.org/10.3928/23258160-20230130-03

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Cavichini M, Bartsch DG, Warter A, Singh S, An C, Wang Y, Zhang J, Nguyen T, Freeman WR. Accuracy and Time Comparison Between Side-by-Side and Artificial Intelligence Overlayed Images. Ophthalmic Surg Lasers Imaging Retina. 2023 Feb;54(2):108-113. PMID: 36780638.

doi: https://doi.org/10.3928/23258160-20230130-03

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Unno N, Lando L, Alex V, Sim PY, Jhingan M, Freeman WR, and Borooah S. Comparison of multicolor scanning laser imaging and color fundus photography in evaluating vessel whitening in branch retinal vein occlusion. Ophthalmic Res. 2022 Dec 8. PMID: 36481649.

doi: https://doi.org/10.1159/000528251

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An C, Wang Y, Zhang J, Freeman WR, and Nguyen TQ. Self-Supervised Rigid Registration for Multimodal Retinal Images. IEEE Transactions on Image Processing. 2022;31;5733-5747.

doi: https://doi.org/10.1109/TIP.2022.3201476

Grondek JF, Huffman K, Lee EJ, Cavichini M, Warter A, P Kalaw FG, Heinke A, Fan R, Cheng L, Sailor MJ, and Freeman WR. Effective treatment of retinal neovascular leakage with fusogenic porous silicon nanoparticles delivering VEGF-siRNA. Nanomedicine (Lond). 2022 Nov;17(27):2089-2108. PMCID: PMC10031552.

doi: https://doi.org/10.2217/nnm-2022-0255

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Wang Y, Galang C, Freeman WR, Nguyen TQ, Cheolhong A. Y. July 2022. Joint Motion Correction and 3D Segmentation with Graph-Assisted Neural Networks for Retinal OCT,” IEEE International Conference on Image Processing (ICIP), Bordeaux, France, 2022;766-770.

doi: https://doi.org/10.1109/ICIP46576.2022.9898072

Damle S, Carleton M, Kapogianis T, Arya S, Cavichini-Corderio M, Freeman WR, Lo YH, Oesch NW. Minimizing Iridium Oxide Electrodes for High Visual Acuity Subretinal Stimulation. eNeuro. 2021 Dec 23;8(6):ENEURO.0506-20.2021. PMID: 34799411.

doi: https://doi.org/10.1523/eneuro.0506-20.2021
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Alex V, Motevasseli T, Freeman WR, Jayamon JA, Bartsch DG, Borooah S. Assessing the validity of a cross-platform retinal image segmentation tool in normal and diseased retina. Sci Rep. 2021 Nov 8;11(1):21784. PMID: 34750415

doi: https://doi.org/10.1038/s41598-021-01105-9

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Zhang J, Wang Y, Bartsch DG, Freeman WR, Nguyen TQ, and An C. Perspective Distortion Correction for Multi-Modal Registration between Ultra-Widefield and Narrow-Angle Retinal Images. Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:4086-4091. doi: 10.1109/EMBC46164.2021.9631084. PMID: 34892126; PMCID: PMC9359414.

doi: https://doi.org/10.1109%2FEMBC46164.2021.9631084

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Motevasseli T, Mohammadi S, Abdi F, Freeman WR. Side Effects of Brolucizumab. J Ophthalmic Vis Res. 2021 Oct 25;16(4):670-675. PMID: 34840689

doi: https://doi.org/10.18502/jovr.v16i4.9757

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Jhingan M, Cavichini M, Amador M, Dans K, Bartsch DU, Cheng L, Chhablani J, Freeman WR. Choroidal imaging biomarkers to predict highly responsive and resistant cases treated with standardized anti-vascular endothelial growth factor regimen in neovascular age related macular degeneration. Retina. 2021 Oct 1;41(10):2115-2121. PMID: 34543243.

doi: https://doi.org/10.1097/iae.0000000000003156

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Wang Y, Warter A, Cavichini-Cordeiro M, Freeman WR, Bartsch DG, Nguyen TQ, An C. Learning to correct axial motion in OCT for 3D retinal imaging. Proc Int Conf Image Proc. 2021 Sep;2021:126-130. PMID: 35950046.

doi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359411/

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Zhang, J. Wang Y, Cavichini M, Bartsch DU, Freeman WR, Nguyen TQ and An C.   Two-Step Registration on Multi-Modal Retinal Images via Deep Neural Networks.  IEEE Transactions on Image Processing, 2021;31;823-838. PMID: 34932479

doi: https://doi.org/10.1109/TIP.2021.3135708

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Zhang J, Wang Y, Kalaw FG, Cavichini M, Bartsch DU, Freeman WR, Nguyen TQ, and An C. Multimodal Global Registration between Ultra-Widefield and Narrow Angle Retinal Images via Distortion Correction Network.Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Mexico, 2021; 4086-4091, Conference on Computer Vision and Pattern Recognition.  

doi: https://doi.org/10.1109/EMBC46164.2021.9631084

Wang Y, Zhang J, Cavichini M, Bartsch DG, Freeman WR, Nguyen TQ, An C. Robust Content-Adaptive Global Registration for Multimodal Retinal Images Using Weakly Supervised Deep-Learning Framework. IEEE Transactions on Image Processing. 2021;30;3167-3178. PMID: 33600314

doi: https://doi.org/10.1109/TIP.2021.3058570

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Wang Y, Warter A, Cavichini-Cordeiro M, Freeman WR, Bartsch DG, Nguyen TQ, An C. Learning to correct axial motion in OCT for 3D retinal imaging. Proc Int Conf Image Proc. 2021 Sep;2021;126-130. PMID: 35950046

doi: https://doi.org/10.1109%2Ficip42928.2021.9506620

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Cavichini M, Dans KC, Jhingan M, Amador-Patarroyo MJ, Borooah S, Bartsch DU, Nudleman E, and Freeman WR. Evaluation of the clinical utility of optical coherence tomography angiography in age-related macular degeneration. Br J Ophthalmol. 2021 Jul;105(7):983-988. doi: 10.1136/bjophthalmol-2020-316622. PMID: 32826223.

doi: https://doi.org/10.1136/bjophthalmol-2020-316622

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Motevasseli T, Jhingan M, Bartsch DU, Singh SR, Alex V, Cavichini-Cordeiro M, Freeman WR. Progress Evaluation in Eyes with Geographic Atrophy and Retina Pseudocyst. Ophthalmol Retina. 2021 Jun;5(6):596-598. PMID: 33217619.

doi: https://doi.org/10.1016/j.oret.2020.11.005

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Borooah S, Papastavrou VT, Lando L, Moghimi S, Lin T, Dans K, Motevasseli T, Cameron JR, Freeman WR, Dhillon B, and Browning AC. Characterizing the natural history of foveal-sparing atrophic late-onset retinal degradation. Retina. 2021 Jun 1;41(6):1329-1337. PMID: 33149097.

doi: https://doi.org/10.1097/iae.0000000000003017

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Alex V, Singh SR, Motevasseli T, Cavicchini M, Jhingan M, Bartsch DU, Cheng L, and Freeman WR. Replacement of lidocaine gel with topical proparacaine anesthesia for routine intravitreal injections: A Comparative Study.  Retina. 2021 Jun 1;41(6):1309-1313. PMID: 33141787.

doi: https://doi.org/10.1097/iae.0000000000003013

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Muftuoglu IK, Lin T, Bartsch DU, and Freeman WR. Influence of vitrectomy on the progression of dry age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2021 Apr;259(4):847-853. PMID: 33064198.

doi: https://doi.org/10.1007/s00417-020-04943-x

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Long CP, Chan AX, Bakhoum CY, Toomey CB, Madala S, Garg AK, Freeman WR, Goldbaum MH, DeMaria AN, Bakhoum MF. Prevalence of subclinical retinal ischemia in patients with cardiovascular disease – a hypothesis-driven study. EClinicalMedicine. 2021 Mar 2;33:100775. PMID: 33842865.

doi: https://doi.org/10.1016/j.eclinm.2021.100775

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Kuppermann BD, Patel SS, Boyer DS, Augustin AJ, Freeman WR, Kerr KJ, Guo Q, Schneider S, López FJ; Brimo DDS Gen 1 Study Group. Phase 2 study of the safety and efficacy of Brimonidine drug delivery system (Brimo DDS) generation 1 in patients with geographic atrophy secondary to age-related macular degeneration. Retina. 2021 Jan 1;41(1):144-155. PMID: 32134802.

doi: https://doi.org/10.1097/iae.0000000000002789

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Xiao Y, Choi KS, Warther D, Huffman K, Landeros S, Freeman WR, Sailor MJ, and Cheng L. A sustained dual drug delivery system for proliferative vitreoretinopathy. Drug Deliv. 2020 Dec;27(1):1461-1473. PMID: 33100053.

doi: https://doi.org/10.1080/10717544.2020.1833382

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Sun Y, Huffman K, Freeman WR, Sailor MJ, Cheng L. Intravitreal safety profiles of sol-gel mesoporous silica microparticles and the degradation product (Si(OH)4). Drug Deliv. 2020 Dec;27(1):703-711. PMID: 32393079.

doi: https://doi.org/10.1080/10717544.2020.1760401

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Sun Y, Huffman K, Freeman WR, Cheng L. Single subconjunctival injection formulation using sol-gel mesoporous silica as a controlled release system for drop-free post-cataract surgery care. J Cataract Refract Surg. 2020 Nov;46(11):1548-1553. PMID: 32818352.

doi: https://doi.org/10.1097%2Fj.jcrs.0000000000000366

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Long CP, Bakhoum MF, Freeman WR. Depigmented Chorioretinal Lesions Following Varicella-Zoster Virus Infection. JAMA Ophthalmol. 2020 Nov 1;138(11):e201652. MID: 33180134.

doi: https://doi.org/10.1001/jamaophthalmol.2020.1652

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Cavichini M, An C, Bartsch DG, Jhingan M, Amador-Patarroyo MJ, Long CP, Zhang J, Wang Y, Chan AX, Madala S, Nguyen T, Freeman WR. Artificial Intelligence for Automated Overlay of Fundus Camera and Scanning Laser Ophthalmoscope Images. Transl Vis Sci Technol. 2020 Oct 20;9(2):56. PMID: 33173612.

doi: https://doi.org/10.1167/tvst.9.2.56

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Wang Y, Zhang J, Cavichini M, Bartsch DG, Freeman WR, Nguyen TQ, and An C. Study on correlation between subjective and objective metrics for multimodal retinal image registration. IEEE Access. 2020 Oct;8;190897-190905. 

doi: https://doi.org/10.1109/ACCESS.2020.3032348

Bantseev V, Schuetz C, Booler HS, Horvath J, Hovaten K, Erickson S, Bentley E, Nork TM, Freeman WR, Stewart JM, Barteselli G. Evaluation of surgical factors affecting vitreous hemorrhage following port delivery system with Ranibizumab implant insertion in a minipig model.  Retina. 2020 Aug;40(8):1520-1528. PMID: 31436674.

doi: https://doi.org/10.1097/iae.0000000000002614

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Khan KN, Borooah S, Lando L, Dans K, Mahroo OA, Meshi A, Kalitzeos A, Agorogiannis G, Moghimi S, Freeman WR, Webster AR, Moore AT, McKibbin M, Michaelides M. Quantifying the Separation Between the Retinal Pigment Epithelium and Bruch’s Membrane using Optical Coherence Tomography in Patients with Inherited Macular Degeneration. Transl Vis Sci Technol. 2020 May 23;9(6):26. PMID: 32821523

doi: https://doi.org/10.1167/tvst.9.6.26.

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Amador-Patarroyo MJ, Lin T, Meshi A, Dans KC, Chen K, Borooah S, Molano-Gonzalez N, Díaz-Rojas JA, Freeman WR. Identifying the factors for improving quality of oral fluorescein angiography. Br J Ophthalmol. 2020 Apr;104(4):504-508. PMID: 31272951.

doi: https://doi.org/10.1136/bjophthalmol-2019-314187

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Lin T, Dans KC, Muftuoglu IK, Meshi A, Amador-Patarroyo MJ, Cheng L, Freeman WR. Factors associated with extended remission in neovascular age-related macular degeneration on pro re nata treatment protocol. Br J Ophthalmol. 2020 Jan;104(1):58-63. PMID: 31302628.

doi: https://doi.org/10.1136/bjophthalmol-2018-313447

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