Current Clinical Trials
List of Current Clinical Research Trials at the Shiley Eye Institute
| Trial | IRB # / Trial Contact |
|---|---|
| An Extension Study to Evaluate the Long-Term Outcomes of Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTE-ROP-1920 Study | 8058085 Nudleman, Eric |
| A Multi-center, Double-Masked, Randomized, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of Atropine 0.1% and 0.01% Ophthalmic Solutions Administered with a Microdose Dispenser for the Reduction of Pediatric Myopia Progression (The Chaperone Study) | 805073 Robbins, Shira |
| A Multi-center, Double-Masked, Randomized, Vehicle-Controlled 12-Month (with a 12-month, Double-Masked Extension) Parallel Comparison of the Safety and Efficacy of 0.1% and 0.2% CBT-001 versus Vehicle, Dosed Twice-Daily, in Patients with Pterygium | 804723 Haw, Weldon |
| Natural History of Retinal Degeneration | 804279 Borooah, Shyamanga |
| Improving Corneal Ulcer Outcomes with Unbiased Pathogen and Antimicrobial Resistance Detection [Protocol Title: capriCORN – Cataloging and Analysis of Pathogens, Resistomes, and Inflammatory-markers in the CORNea] | 804035 McClean, Esmeralda |
| Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated with Variants in the RPGR gene | 802624 Borooah, Shyamanga |
| Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of Xlinked Retinitis Pigmentosa Associated with Variants in the RPGR gene | 802611 Borooah, Shyamanga |
| A Phase 2b, Randomized, Double-Mask, Placebo-Controlled, Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Linsitinib in Subjects with Active, Moderate to Severe Thyroid Eye Disease (TED) | 802493 Kikkawa, Don |
| A Double-Masked, Randomized, Controlled, Multiple-Dose Study to Evaluate the Efficacy, Safety, and Tolerability of QR-421a in Subjects with Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene with Early to Moderate Vision Loss | 801888 Borooah, Shyamanga |
| Seasonal Conjunctivitis Outbreak Reporting for Prevention and Improved Outcomes | 801770 McClean, Esmeralda |
| A Phase 1/2A Study to Assess the Safety and Efficacy of OCU400 for NR2E3-Related Retinitis Pigmentosa | 801761 Borooah, Shyamanga |
| Phase 3 Randomized, Controlled Study of AAV2/5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated with Variants in the RPGR gene | 801491 Borooah, Shyamanga |
| A Phase 3, Randomized, Open-Label, Multi-Center Study of a Recombinant Adeno-Associated Viral Vector (AAV5-OPTIRPE65) for Gene Therapy in Adults and Children with Confirmed Biallelic RPE65 Mutation-Associated Retinal Dystrophy | 800728 Borooah, Shyamanga |
| Vista: A Phase 2/3, Randomized, Controlled, Masked, Multi-center Study to Evaluate the Efficacy, Safety and Tolerability of Two Doses of AGTC-501, a Recombinant Adeno-associated Virus Vector Expressing RPGR (rAAV2tYF-GRK1-RPGR), Compared to an Untreated Control | 210119 Borooah, Shyamanga |
| A Phase 4, Randomized, Double-masked, Placebo-controlled, Multicenter Trial to Evaluate the Efficacy and Safety of TEPEZZA® in Treating Patients with Chronic (Inactive) Thyroid Eye Disease | 201707 Liu, Catherine Yunxiang |
| AGN-151587 Single Ascending Dose Study in Participants with LCA10-IVS26 | 191760 Borooah, Shyamanga |
If you would like more information on any particular trial, please email shileyclinicaltrials@health.ucsd.edu or visit our contact page.